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Filet mignon! To many peoples' minds, the words themselves speak of excellence, good living and expensive taste. No wonder. Ca

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

refully selected and expertly cut, filet mignon is a steak lover's dream.

Filet mignon is a boneless steak that is cut from the

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

tenderloin of the cow, which, as its name implies, yields the tenderest meat.

The filet itself is usually cut into portions bet

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

een 1 and 2 inches in thickness. Oftentimes, stores sell such portions pre-wrapped with bacon. The reason for this is that file

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

mignon does not contain as much fat marbling as bone-in steak cuts generally do; the bacon, then, substitutes for the missing fa

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

.

If you prefer your marbling to be natural, or you simply don't eat pork, then look for filet mignon that is pink rather than

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ed--the lighter the color the better, in other words. Lighter color=more marbling.

One key point to remember when cooking filet

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

mignon, whether you broil, roast, grill or pan fry it, is to use high heat in the process. A second key point is not to cook it

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

oo long; filet mignon is particularly susceptible to drying out as it cooks.

Keeping those two key points in mind, almost any s

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

eak recipe will work for filet mignon. Cookbooks and the Web are overflowing with imaginative things you can do with this royal

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

cut of beef. If you've never cooked filet mignon, though, here are two basic recipes to get you started:

Grilled Filet

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

Mignon

Ingredients

4 filets mignons

Salt

Black pepper

Directions

Heat grill. Grill

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

filets mignons for 3 to 5 minutes per side, which will cook them to medium or medium-rare doneness. Add salt and pepper to tast

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

. Serve.

Note: Connoisseurs will tell you that filets mignons can only be properly appreciated medium-rare or even rare. I te

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

d to agree. But if you really can't stand the thought of eating steak that pink, feel free to cook longer. Again, start with h

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

gh heat so as to minimize the time needed to reach your preferred state of doneness.

Sauteed Filet M

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

gnon

Ingredients

4 filets mignons

Salt

Freshly ground black pepper

2 teaspoons fresh, chopped

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

osemary

Cooking oil

Directions

Season the filets mignons with the salt and pepper, then sprinkle rosemary over them.

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

Heat a little oil in a skillet over medium to high heat. Place the meat in the skillet and fry for 3 to 5 minutes per side (for

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

edium-rare doneness).

By the way, a red wine such as cabernet sauvignon or burgundy makes a great accompaniment to filet mignon

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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