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If you decide to enter the show ring with your Shih Tzu one of the greatest benefits will mostly likely be an enhanced appreciation for the sheer beauty of the Shih Tzu. Just think about it, even if you only

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

own one Shih Tzu yourself, at the shows you will see dozens and hundreds of Shih Tzu. Most of these Shih Tzu will be in prime health and perfectly groomed. By observing, and asking questions when the oppo

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

tunity arises, you will begin to see some of the differences in the Shih Tzu that you may not have noticed without going to the shows. You may be surprised at how much you learn about the Shih Tzu and maybe

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

even your own Shih Tzu during these events.

Shih Tzu showing should also teach you some facts about yourself. You might think you will be a nervous wreck on stage in front of all those people, but then find

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

yourself not at all that nervous, but full of pride and poise that your Shih Tzu shares in some of the qualities of the other Shih Tzu. Or you might feel like you will never lose it at a Shih Tzu dog show no

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

matter what happens, and then the first time, someone else says a slightly less than kind remark about your very own beloved Shih Tzu, that you just fall to pieces and tear out in a rage at that person. If y

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ou have never competed in organized sports before, you might be surprised at how great your desire to “win” actually is, and you may have to learn to curb this a little. You will need to learn right from the

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

start of things that no matter what happens at the Shih Tzu show dog you need to learn how to be a “good loser.” Not every Shih Tzu will be the winner. And it might just be your Shih Tzu that does not win.

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

In your heart, you must always realize your Shih Tzu is not and never could be a “real loser.” However, in the ring, he is just another “contestant,” to the judge who is trying to be fair to all who have en

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ered the competition.

As with many competitive sports, dog or Shih Tzu showing will present you with an odd combination of friendships versus mean-spiritedness’ poor losers. Don’t be one of the poor losers.

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

Try your best to be one who will be a friend. If everyone practice being “the friend” rather than the mean-spiritedness and poor losers the dog shows would be much more beneficial and fun for all concerned.

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

During the time spent waiting at a Shih Tzu dog show, rather than sitting and working yourself up into a nervous wreck, try to make friends with those around you. Try to start a genuine conversation with t

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ose around you. If you have very good past Shih Tzu show dog experiences, now is not the time to go on and on about yourself, your many time winning Shih Tzu dogs and wonderful experiences in the ring. In o

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ther words: “Do not sit and brag.” Offer advice when appropriate and always aim toward the good of the Shih Tzu and the dog shows in general.

As time goes on if you continue showing your Shih Tzu you will

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

e running into the same people. Try to start out on the right foot at these events. Of course, you will not be compatible with everyone and there are always those people who cannot win as friends for nothin

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

in this world. For that group, just try to steer away, and find those you can become friends with. It helps to have friends, and if your friends have Shih Tzu that wins over your Shih Tzu, you can celebrat

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

e their achievement instead of grieving your loss.

If you are very fortunate and have a genuine desire to learn, you can probably find a good mentor at the Shih Tzu show dogs. When you show a real interest

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

n the Shih Tzu and a sincere desire to learn all you can about showing the Shih Tzu to your best and improving the Shih Tzu breed, you may just attract one of the “old-timers” or even someone younger with mor

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

e experience that would be delighted to become your mentor. Sometimes when people have a lot of knowledge about a subject they just love sharing that knowledge with others who are as interested as they are i

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

the same subject.

A compatible and knowledgeable mentor is probably the most important step in getting into showing dogs and the Shih Tzu successfully.

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tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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