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Are you thinking of proposing this Valentine’s Day? If so, here are a few things you need to know.

A proposal shoul

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

d be done privately, just between the two of you. Yes, you see people on the news proposing in front of thousands of people or m

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ybe a friend proposed in front of dinner guests at some sort of gathering. Occasionally you might catch someone proposing at a r

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

staurant or some other public place. But it’s not a good thing.

The reason you shouldn’t do this is because it’s not fair t

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

the person you’re proposing to. She will not feel free to say "no", if in fact she isn’t ready for marriage. Or maybe she needs

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

time to think about the question. She’ll feel rushed into an answer that may not be correct. You don’t want her to marry you jus

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

because she felt pressured into it; it’s a disaster waiting to happen. Start your new life together on the right foot.

If

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ou still think you need to include friends and family, you can throw an engagement party after she says "yes", and both of you c

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

n announce the good news together.

Here are a few romantic ideas for popping the question:

Have an indoor picni

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

complete with picnic blanket, basket and fresh summer flowers. Fill the basket with all sorts of picnic foods and the ring box

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

When she starts taking food out of the basket, she will come across the ring box and bam, you can pop the question.

Weathe

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

permitting, you can go for a walk to a secluded area and when you sit down for a rest, pull the ring from you pocket, get on on

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

knee and ask your love to marry you.

Make a romantic dinner for two. Use roses, candles, soft music, wine glasses and nic

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

dishes to decorate. If you’re not a good cook, buy dinner for two and put it on your own dishes at home. Propose to her during

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

inner.

Plan an evening out, do anything from dinner, dancing, go to a show or go for a drive. Because it’s Valentine’s Day,

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

add things to your evening like flowers and other Valentine’s Day things. Then when the evening is over, pull the ring out and p

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

p the question.

Go for wine tasting and a tour at a winery. Buy a bottle of wine and when sharing it together give her the

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ing box to open. Ask her or have a note or poem in the box with the ring asking her to marry you.

Plan a romantic weekend g

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

taway and propose when the moment feels right.

Whichever way you choose to propose, make it heartfelt and have fun. After a

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

l, you will be spending the rest of your lives together.

Congratulations and I hope you have a long and happy marriage.

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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