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Have you taken a good look in your refrigerator, lately? Your mother-in-law’s Meatloaf Surprise started living up to it’s name two weeks ago. Month-old leftovers are now candidates for J

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

unior’s next science project.

Don’t let your food decay behind the Brita pitcher! Follow these tips to save you time, space, and wasted food:

Purge

Grab your garbage can, position it

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ext to your refrigerator and purge it of all spoiled food. Look for tin foil sculptures and anything that wasn’t green BEFORE you bought it. Keep repeating to yourself, ‘When in doubt, t

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

hrow it out.’

Make it shine!

Use some elbow grease and give those shelves, drawers, and crisper a good cleaning. It’s not easy to organize jars and containers if they’re sticking to th

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

shelf... Clean one shelf at a time, starting with the top one. All crumbs, liquid, and unidentifiable objects that don’t make it into your paper towel will land on the shelf below, whic

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

you will be cleaning next. Once you’ve finished cleaning the bottom shelf/drawer, continue with the inside door until you’re satisfied with the job.

Group ‘em

Group similar foods toge

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ther. For example, place drinks on one shelf, small snacks in a drawer, and fruits/veggies/salad products in the crisper so you are not constantly ‘hunting down’ the food you want/need a

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

that moment. This arrangement saves you time and makes retrieving food come mealtime a less arduous task.

* Pay attention to the height of your jars and bottles. It is easier to spot y

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ur food and drink if you put large/tall jars towards the back of the refrigerator and smaller ones in the front. You’ll never see that container of yogurt if it’s trapped behind a family

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

-sized jar of spaghetti sauce. That’s money (and spoiled yogurt) down the drain...

Give ‘em a home

Growing up, our refrigerator always had what I called ‘The Cheese Box.’ Instead of ha

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ing that flat package of Swiss cheese teetering atop a jar or the shredded mozzarella accidentally flattened by a side of beef, all the cheeses would ‘live’ together in one plastic conta

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ner. We always knew where to find them and whether or not we were running low. This is a perfect solution if you have small, like items floating around your fridge. If you have young chi

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ldren, you can create a similar container for each child and fill it with healthy snacks, punch boxes, or a loving note. This keeps ‘little fingers’ from rummaging the shelves and you ca

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

control what goes into their ‘snack box.’

Give ‘em a quality home

Whether they hold groupings of food or greasy leftovers, your containers should work for you and not against you. Con

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ider spending a few cents more for quality containers. Lids are less likely to get stuck or fly off. You don’t want to spend your time cleaning the floor or removing stains from your shi

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

rt because your container failed to do it’s job. Choose transparent or translucent containers—they allow you to see exactly what’s inside—no surprises!

Give ‘em the same home

Keep your

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

refrigerator organized by making your best attempt to return food and drink to the ‘home’ you’ve created for it. Haphazardly throwing your groceries in the fridge may save you time when

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ou come back from the store but it will cost you precious minutes at meal planning and preparation time.

In order to keep it clean and uncluttered, purge your refrigerator as part of yo

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ur weekly routine. I recommend tackling this task on the night before your garbage pick-up day. Regularly disposing of smelly substances, rotting vegetables, and other items that have ov

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

rstayed their welcome will keep your fridge in tip-top shape. With determination, patience, and the right tools your refrigerator can become an organized and functional area of your home

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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