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Flying is often a person’s greatest fear. With the recent Air France crash at the Toronto Pearson Airport, some flier’s stre

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ss may be at an all-time high. However, it is possible to practice stress management solutions while flying. Hamilton-based

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ark McGregor, who is a stress management trainer and consultant, believes that we should use our HEADS (Humour, Exercise, Av

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

id, Delegate, Seek) to manage our flying stress. Mark comments, “Some air passengers unnecessarily worry and become overwhel

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ed when traveling on airplanes which causes increased personal stress. It’s not enjoyable for themselves or the people they

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ravel with. Chances are you will not be able to totally eliminate flying stress. However, with practical stress management s

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

lutions, you will be able to reduce your stress and enjoy your flying experience more.” The experienced air passenger and tw

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

o-time stress-induced heart attack and arrhythmia survivor offers some air-travel stress-relief solutions:

• Humour is the

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

est medicine. Pack some comic strips, a book that can make you laugh or a funny photo in your travel case. When feeling over

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

helmed, pull out your reading material and let the comical content take your mind off of flying.

• Exercise is possible on

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

n airplane. You do not require a sweaty twenty-minute workout to gain the benefits of exercising for stress-relief. Be sure

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

o pack a stress-relief ball that you can squeeze away at when things get bumpy. Take a brief stroll in the isle when the cab

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

n seatbelt warning lights are off.

• Avoid conversations with toxic people. You know the crash-n-burn type that believes ev

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

rything about their flying experience is wrong. Tune them out by bringing your own music player and headphone set. Or simply

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

plug in your headphone set into your laptop computer and play all your favorite hits. You may want to avoid playing “Spirit

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

in the Sky!”

• Delegate tasks to the flight attendants. Ask nicely, and you may be surprised what you get. Ask for a warm b

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

anket or a soft pillow to rest with. On longer-haul flights, ask for middle-row seating so you can stretch out on vacant sea

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

s on less populated flights.

• Seek the right frame of mind. Flying has always been one of the safest methods of travel. Si

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

back and relax as trained professionals add to the comfort of your flying experience. Know that your pilot has logged in nu

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

erous hours of flying time. Feel secure with the fact that security procedures have increased for your protection and safety

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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