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Overview
Athens is one of the most historical cities in the world, and the architecture of the city is a tell-tale sign of the centu

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ries of history that have been lived out within its walls. Athens is surrounded on three sides by mountains, and, on the fourth side, the city e

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

xtends to the coast of the Mediterranean Sea. The area just off of the face of the sea is Pireas, the city’s harbor. All of the city streets lea

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

d to Pireas. Besides being surrounded by mountains, there are also eight hills within the city, most notably Acropolis and Lykavittos. The city’

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

center, Syntagma Square, is the city’s business district, home to most of Athens’ hotels, restaurants, bars, and banks. The Plaka, seated at th

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

e foot of the Acropolis, is the city’s historic district with distinct remnants of the city’s Roman past. The top of the Acropolis is commonly r

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

eferred to as the High City, the location of many marble temples dedicated to Athena. Another area worth mentioning is Psiri, the city’s industr

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

al district, home of many local bars, cafes, and corner shops.

Sightseeing Attractions
The most historical site in Athens is defini

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

tely Acropolis, home of the Parthenon, the Erectheion, and the Temple of Athena Nike. However, there are many other sites in Athens that have ju

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

st as much historical value, though they are tucked in amongst the grayness of the city’s modern architecture. The best way to see everything th

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

t Athens has to offer is to start in Acropolis and work your way down. A walk through the areas at the foot of the Acropolis -- Anafiotika, Plak

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

a, Monastiraki and Thiseio -- will merit a wealth of historical buildings, from remnants of the Roman Era to art deco buildings from the late 20

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

th century.

Museums
Because Athens is a city with such a long and great history, its museums are packed with artifacts and arts tha

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

t no other city in the world has to offer. There are four major museums that every tourist should visit, though there are many more that are not

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ble. The four main museums are the Acropolis Museum, the Benaki Museum, the National Archeological Museum of Athens, and the Museum of Cycladic

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

Art.

Nightlife
For upscale shopping, head for Kolonaki, just outside of Syntagma Square, or, for less upscale and more original sou

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

venirs, check out Ermou Street. Most of the city’s restaurants are clustered around Syntagma Square; however, Psiri has recently been earning a

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ame for itself as far as dining and drinking is concerned. While the businesses in Syntagma Square are fairly tourist-oriented, the businesses a

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

round Psiri are more artsy and less expensive. The smaller shops often have the best food as well. Psiri is also a great area for nighttime drin

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

king and socalizing; however, the club district is located on the harbor, and many of the parties move out to the beach during the summer months

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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