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Albatera – Lying to the north of the village of Cox, Albatera is another of the traditional Spanish towns of the Vega Baja district of the Alicante province, its white-walled houses sit quietly on wide, palm-lined streets giving it a peaceful, pleasan

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

t feel. Life in Albatera centres mainly around the Town Square, the location for many of its fiestas and celebrations, also in the Town Square there is an attractive church with a stunning baroque style door, intricately carved in stone. The popular A

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

lbatera Golf and Country Club is some 5 km away from the town.

Algorfa – In the middle of citrus farming country, Algorfa is a small village with a big heart, its warm friendly people always have a smile for visitors. Located close to the larger vill

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

age of Almoradi, Algorfa is most noted for its La Finca Golf Club, with its wonderful par 72 golf course designed by Jose Gancedo. Just outside the village is an unusual nineteenth century neo-gothic church. Algorfa’s traditional market is held every

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

Sunday and is a great place to spend an hour or two hunting for bargains and locally grown fresh produce.

Orihuela – The capital of the Vega Baja region of the Alicante province, Orihuela is an ancient town with a long and distinguished history. Thou

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

gh there were settlements in the area during the Bronze Age, Orihuela came into its own during the Roman occupation when it was known as Auraiola, later an important headquarters for the Moors under Teodomiro it was re-conquered for the Christians in

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

1296. Recognised for its large number of beautiful churches, palaces and monasteries, Orihuela also has several museums that are worth visiting while in the town.

Callosa de Segura – Overlooked by the surrounding Sierra de Callosa mountains, the medi

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

m sized town of Callosa de Segura features some of the oldest buildings in the Alicante province. The land around Callosa de Segura, irrigated by the Segura river is rich and fertile, and perfect for the growing of vegetables and citrus fruits. One of

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

its most interesting buildings is the Saint Roque Hermitage which took over 200 years to construct (1579-1798) and was built on the exact spot where the Patron Saint Roque is said to have appeared. Also noted for hemp and hemp products Callosa de Seg

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ura has a Hemp Museum which describes the production of hemp from seed to final product.

Redovan – A busy little town located in the Vega Baja region of the southern Costa Blanca, Redovan was founded by the Moors during the Arab occupation (8th to 13

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

th Centuries). Situated just 7 km from the main town of Orihuela, Redovan sits at the foot of the Sierra Segura, a beautiful mountain area covered in pine trees. Over the centuries Redovan has been an important area for the production of ceramics and

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

is also known for its hemp and hemp products. Notable in Redovan is the old city hall with its hand crafted clock tower dating from the 18th Century.

Vega Baja – The most southerly district of the Alicante province, the Vega Baja has a name which mea

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ns ‘Low Fertile Valley’, an important area for the growing of fresh produce, citrus fruits in particular, it also has a beautiful coastline with some fine beaches and popular resorts. The capital of the district is the town of Orihuela and the largest

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

of its coastal towns are Torrevieja and Guardamar del Segura, where superb white, sandy beaches are lapped by the sparkling, tranquil waters of the azure blue Mediterranean Sea.

Benferri – The delightful village of Benferri is ideally located in a t

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

iangle between Alicante, Murcia and Orihuela, it is one of the Vega Baja (Low Fertile Valley) villages situated in rich citrus farming country. The land around Benferri was irrigated first by the Romans and later by the Arabs during the Muslim occupat

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ion (eighth to thirteenth centuries) making the soil perfect for the growing of fruit and vegetables. The original village was set up by James Rocamora in 1494, he built 29 dwellings for 29 families to live and work in the village – his work was carri

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ed on by his son Jeronimo de Rocamora, the church of San Jeronimo still stands today.

Formentera del Segura – Originally a Moorish village, Formentera del Segura was conquered by the Christian king Jaime I (‘The Conquistador’) in 1242, the village ch

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

anged hands a number of times over the prevailing centuries until 1730 when it came under control of Nicolas P?rez de Sarrio (The Lord of Formentera), who gave the village its current name. Largely destroyed by the great earthquake of 1829, Formentera

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

del Segura was re-built by 1840 culminating in the building of the parish church. Relying mostly on agriculture and citrus farming for its survival Formentera del Segura benefits from an irrigation system put into place by the Moors centuries ago. On

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

e of its most popular fiestas is ‘The Day of the Bicycle’ featuring a race involving many of its inhabitants.

Here we have to end our short trip to the Costa Blanca village of Albatera and its neighbouring towns and villages of the Vega Baja district

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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