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Social Space - Exploring the Vibrant Karoo
At a first glance, the arid Karoo which transfrontiers the north-eastern part of the Western Cape and southern parts of Northern Cape, looks deserte
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
d and barren, but if you look closely you will see that there are numerous welcoming towns inhabitat by people who have their own stories to tell, t
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
whoever wishes to hear it…
The name ‘Karoo’ comes from karusa a Khoi word that means ‘dry’, ‘barren’ or ‘thirsty land’ and this is exactly
The name ‘Karoo’ comes from karusa a Khoi word that means ‘dry’, ‘barren’ or ‘thirsty land’ and this is exactly
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
what you would think as you first enter the Karoo. It is hard to imagine that these vast dry plains were once an inland sea, with lush green vegetat
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
on and huge mammals roaming its shores. Its only after the Gondwanaland break-up approximately 200million years ago, that the region turned into the
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
semi-desert area we know today.
The “Oasis of the Karoo”, Beaufort West, is the oldest town in the region. With a colourful history his typical
Many choose Beaufort West as a destination simply to explore the ecology and to walk through the streets and have a good look at the beautiful old
The “Oasis of the Karoo”, Beaufort West, is the oldest town in the region. With a colourful history his typical
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
platteland town was once inhabited by the Bushman and many of their rock art sites can still be seen on sourrounding farms and nearby Nelspoort.
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
Many choose Beaufort West as a destination simply to explore the ecology and to walk through the streets and have a good look at the beautiful old
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
buildings that display a mixture of architectural styles dating back to the mid nineteenth century. Most of the little towns of the Karoo have their
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
own unique style of architecture, which deveoped around simple structures with prominent covered verandahs as protection against the harsh sun.
On
On
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
building that you cannot miss is the Neo-Gothic Reformed Church on the N1; it was built in 1892 and designed by James Bisset. This beautiful church
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
is situated on what is affectionately known as “Amen Corner”, with its spire forming the focal point of town. Another landmark on the N1 is the jai
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
house that stands in the middle of the road, and no one to this day really knows why a jail house was built here.
Be sure to explore the isolated
Be sure to explore the isolated
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
but welcoming villages of the region which sit between the flat-topped koppies in desolate valleys. Names like Vosburg, Griquatown, Witput and Three
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
Sisters, speak of fascinating stories that await to be told in vibrant Karoo colour.
To the south of the Karoo is the 75 000ha Karoo National Park
To the south of the Karoo is the 75 000ha Karoo National Park
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
where one can see the endangered Riverine Rabbit and the Black Rhinoceros. The Quagga, which until recently was thought to be extinct has also been
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
resurrected’ and roams freely on the grounds of the park. It is also home to lots of indigenous buck, mountain zebra, wild ostrich and five tortoise
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
species, and for the birders there is an abundant range of species that call the park home.
Go on the fascinating fossil trail and learn more abou
Go on the fascinating fossil trail and learn more abou
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
the fossils that were discovered in this area. Round off your exploration with a scenic drives, take a challenging hiking trails into the koppies,
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
go biking in the mountain trails or take a leisurely stroll through town.
With so much to do and discover, the Karoo is a top-class eco-destination
With so much to do and discover, the Karoo is a top-class eco-destination
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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