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The biggest secret of street fighting success revealed!

Most people start doing self defence because they don’t want to get hit in the head but isn’t it interesting that most people afte

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

r years of martial arts training still struggle to deal with a variety of random strikes being thrown at their head. Sound familiar?

So why is that?

The first thing you need to address

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

is the teaching methods in which the material you have been taught has been delivered too you. If you are still not confident with randomization drills after years of training, it is time

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

to question your instructors teaching methods.

The simple answer is that you have been taught incorrectly. In fact, most self defence systems across the globe teach people incorrectly s

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

don’t feel bad. Most self defence systems teach you in a controlled relaxed state, in an environment where your brain has conscious thought, so that you have the advantage of being able

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

to either pre-determine the attack or know exactly what technique is coming at you. You have time to consciously assess the situation.

Unfortunately in a real situation or in drills of r

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

andomization, the brain slips into sub-conscious thought. That means that whatever you have trained most against, that stimulus will come out without conscious thought. In other words wi

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

thout thinking about it.

Here is the catch 22. How many times have you sat there thinking it’s going to be a jab, cross, hook, uppercut etc? How many times have you focused on the techni

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ue coming at you? This sort of thinking can possibly get you killed.

So what is the answer?

There are two main secrets that I will reveal too you. They are simple and they work. It has

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

taken me over 18 years to understand and develop this simple theory. It isn’t something that was ever presented to me like this, but I wish it was.

Secret 1: Combative footwork- It is y

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

our base that must move before all else. Train it so it is in your subconscious memory. Be able to evasively maneuver in any given direction, left and right. Remember someone can’t hit yo

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

u if you’re not there to hit.

Secret 2: Ok this is the main one. Study to defend against the 4 main angles, not the technique. Here is the basic theory for hand strikes. Learn to move

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

nd counter straight, around, up and down both left and right handed. I hear what you’re saying though. What about the technique? It doesn’t matter about the technique. It’s only the angle

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

of delivery that matters.

Always remember “the body only functions on a few angles but there are many hundreds of techniques that apply to those angles”

Let’s look at the straight angl

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

e for example. It can be – cross punch, extended uppercut, jab, five finger spear, vertical fist punch, palm strike and the list goes on.

By countering just the angles of delivering we l

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

essen the amount of things we need to concentrate on. Remember, the brain is like your desk at work. If you have everything neatly organized its quick and easy to grab information when ne

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ded. If it’s cluttered and messy it will take you a lot longer to find the information.

The theory is easy and works. Think less, react more. Remember the brain consciously only thinks a

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

bout 7 things at a time. So keep it simple.

Here is a basic training theory to rapidly increase your ability to defend against random attacks.
 Practice your 8 directions o

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

f movement
 Practice countering all angle strikes in isolation first
 Practice moving your body out of the way of strikes being delivered at you.
 P

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ractice countering random strikes using your base and defensive tactics
 Practice countering random strikes with full combat scenarios

Until next time stay safe

Glenn Zwier

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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