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Here’s a question I sometimes ask when giving a golf lesson. What do pro golfers Jose Maria Olazabal, Tiger Woods, and Sergio Garcia all have in common? Answer: They don’t hit into trouble often, but when they do, their s

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

hort games save them, and accurate chipping is one of the most potent weapons in their short game. In fact, most players with low golf handicaps chip accurately.

The chip shot is one of the easiest shots to learn in golf

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

It’s also one of the most crucial. In medal play, accurate chipping can save you one or two strokes on a hole, sometimes more. In match play, it can be the difference between winning or losing a hole or a match. And in

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

player rankings, it’s often what separates players with high golf handicaps from those with low ones.

Confidence, experience, and imagination all contribute to accurate chipping. But so does good technique. Below are 6 k

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ys to accurate chipping:

1. Decide on a landing spot
2. Use a one-piece takeaway
3. Maintain weight on front side
4. Keep hands ahead of clubhead
5. Hold the clubhead
6. Accelerate the cl

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

b through the ball

Professional golfers play a wide variety of shots around the green. One player may use a sand wedge to chip with from a certain spot, while another hits a 9 iron from the same spot. Regardless

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

of what club they use, they all pick out a landing spot before hitting the ball, which they play the ball off their left heels.

Picking a landing spot is imperative, as I’ve mentioned in my golf tips. So is using a one-

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

iece takeaway. In fact, it’s as important in chipping as it is in driving. Since the shot is hit mostly with your arms and hands, it requires little or no weight transfer, so place your weight on your front side and keep

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

it there. Also, keep your head still when hitting the ball.

The backswing is important as well. The length determines the length of the shot— the longer the backswing, the longer the shot. Be mindful of your backswing wh

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

n chipping. Also, take the club back smoothly and slowly, allowing your wrists to hinge naturally.

When committing to the downswing, make sure your hands stay ahead of the clubhead to ensure crisp ball-before-turf contac

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

. The objective is to slide the blade of the clubhead under the ball, taking only a sliver of turf in the process.

Also, don’t allow your right hand to cross over your left through impact. Known as “holding the clubhead,

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

” the technique keeps the clubface open, creating a high shot that lands softly on the ground.

In my golf tips I tell players to finish in balance and with their hands slightly higher than the height of their backswing.

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

oing so indicates that the golfer has accelerated the clubhead through the ball. The motion is similar to throwing a ball underhanded, which I sometimes have players do in my golf lessons to get a feel for the shot.

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ong>Change the Club Drill

The change-the-club drill is an excellent exercise for practicing your chipping. It simulates hitting from the fringe of the green or fairway when your landing spot is about 3 feet away

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

but the ball needs to roll about 15 feet or more. The idea is to hit various clubs with the same motion to learn reaction and distance. It’s a golf lesson in itself.

Choose a green that’s a challenge. Maybe it has some

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

alleys in it or maybe a significant side slope. Then pick a spot about five feet off the green and drop a ball. Set one club about two and a half feet behind the ball and another club about two and a half feet in front of

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

the ball to give you an idea of distance. With the identical motion hit chip shots with each of four clubs—the sand wedge, 9 iron, 7 iron, and 5 iron.

After hitting the ball you’ll notice that the ball runs father as th

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

clubs get lower and lower. Pick the club that will land the ball about two to three feet on the green and run the rest of the way to the hole. Remember to factor in slope and/or the speed of the green when selecting a cl

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ub.

Using different clubs will give you a better feel for which club runs the ball farther and which lands softly and stops, making club selection somewhat easier next time you play.

Keep practicing this drill until can

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

get within a foot of the pin every time. By then, you should start seeing the benefits of accurate pitching not only in better scores but also in a lower golf handicap. And that will keep you practicing for better results

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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