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Social Space - How to Train The Energy Systems for Maximum Efficiency
In order to train with maximum effectiveness it is important to understand what the demands of your sport or activity are. This is accomplished by applyi
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
ng the appropriate energy system(s) to your training. The pace of your sport or activity dictates the energy system(s) involved. Our bodies use a compoun
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
, ATP (adenosine triphosphate), as its energy source. When we run low on ATP we have to replenish it and we do so by utilizing the energy systems.
The e
The e
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
nergy systems are categorized into anaerobic and aerobic systems. There are 2 energy systems that are anaerobic, the phosphagen system and the lactic aci
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
system (also sometimes referred to as anaerobic glycolysis). The third and final energy system is aerobic and is called the aerobic system. All three en
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
rgy systems are always in operation no matter what sport or activity we are performing. While all 3 systems are always in operation it is the percentage
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
of each system being used that changes depending on the sport or activity. The contribution of each system depends on such factors as intensity, duration
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
and rest intervals.
The phosphagen system is dominant during activities of short duration, high intensity and require longer rest periods. These includ
The phosphagen system is dominant during activities of short duration, high intensity and require longer rest periods. These includ
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
e maximum effort activities that last less than 30 seconds such as jumping, sprinting, plyometrics, and fast burst sports to include football, basketball
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
and volleyball.
The lactic acid system allows for activities of longer duration than does the phosphagen system. Maximum effort activities between 30 s
The lactic acid system allows for activities of longer duration than does the phosphagen system. Maximum effort activities between 30 s
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
conds and 4 minutes involve this system although there are contributions from the phosphagen system and the aerobic system and this again depends on the
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
duration. The closer the activity is to being 30 seconds in duration the more the phosphagen system is involved as well. The closer the activity is to 4
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
inutes the more the aerobic system is involved.
The aerobic system allows for more enduring activities such as those over 4 minutes long. Most sports ut
The aerobic system allows for more enduring activities such as those over 4 minutes long. Most sports ut
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
ilize primarily the phosphagen system with moderate to high contribution from the lactic acid system. In these types of sports the aerobic system is invo
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
ved but the contributions are very minimal. Sports that rely mostly on the aerobic system are long distance type sports such as cross country skiing, lon
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
distance track and field events, running marathons, etc. In these types of sports the phosphagen system is involved but the contributions are very minim
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
al.
Once the demands of the sport or activity are determined they need to be trained according to the appropriate energy system(s). Factors that need to
Once the demands of the sport or activity are determined they need to be trained according to the appropriate energy system(s). Factors that need to
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
be analyzed include: duration of the activity, intensity, and rest intervals. Each sport and activity needs to be individualized and the appropriate para
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
meters set up. Those parameters include the duration of each series of plays, how much effort goes into each play and how many are involved, and the amou
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
t of rest period involved between series. By approaching the training in this manner you avoid training the wrong energy systems for the particular sport
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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